CORRELATION BETWEEN EARLY AND LATE RADIOIODINE THYROID UPTAKE IN NORTHEASTERN THAI GRAVES' DISEASE PATIENTS
Keywords:
Correlation, Thyroid uptake, Graves' disease, Radioiodine treatmentAbstract
A retrospective study was undertaken at the Department of Radiology, Faculty of Medicine, Khon Kaen University to determine the correlation between early (3-hrs) and late (24-hrs) radioiodine (131I) thyroid uptake in hyperthyroid Graves' disease patients who were referred for the first 131I treatment. Nine hundred and sixty-nine patients residing in the Northeastern Thailand were enrolled into the study. Their clinical background regarding age, sex, province of residence, indication for 131I treatment, and estimated thyroid gland weight were presented. Thyroid uptake test results of all subjects were analyzed for the correlation between early (Eup) and late (Lup) uptake value. Fairly good correlation between Eup and Lup was found (r=0.6, P<0.001). The best fitted regression equation was the logarythmic model: Lup =7.8 + 17.3 In Eup. These data are useful in the prediction of 24-hrs 131I uptake value from the 3-hrs value in order to reduce a visit in performing thyroid uptake test before 131T treatment.
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