ESTIMATION OF GLOMERULAR FILTRATION RATE IN RENAL TRANSPLANTED PATIENTS: COMPARISON BETWEEN 99m TECHNETIUM DTPA GAMMA CAMERA TECHNIQUE AND PLASMA CLEARANCE TECHNIQUE
Abstract
OBJECTIVE: To find the correlation of glomerular filtration rate (GFR) derived from 99mtechnetium diethylenetriaminepentaacetic acid (99mTc DTPA) renography with gamma camera technique and plasma clearance technique in renal transplanted patients and to find the relationship between GFR values from the two techniques.
DESIGN: Descriptive study design with prospective data collection.
SETTING: Department of Radiology, Srinagarind Hospital, Khon Kaen University.
MATERIALS AND METHODS: Ten renal transplanted patients (12 studies) were enrolled into the study between October 2004 and July 2005. GFR was estimated by two different methods, gamma camera technique and plasma clearance technique, using 99mTc DTPA. GFR values derived from the two methods were correlated. The relationship between GFR values from the two techniques is then determined.
RESULTS: We found that there was a fair correlation of the GFR values between the two techniques (r= 0.69).
CONCLUSION: Although the GFR value from gamma camera technique may be lower than that of the standard plasma clearance technique, GFR by this method is reliable enough in determining renal function in patients post renal transplantation.
Downloads
Metrics
References
Price M. Comparison of creatinine clearance to inulin clearance in the determination of glomerular filtration rate. J Urol 1972; 107(3): 339-40.
Jagenburg R, Attman PO, Aurell M, Bucht H. Determination of glomerular filtration rate in advanced renal insufficiency. Scand J Urol Nephrol 1978; 12(2):133-7.
Brochner-Mortensen J, Rodbro P. Selection of routine method for determination of glomerular filtration rate in adult patients. Scand J Clin Lab Invest 1976;36(1):35-43.
Sawyer WT, Canaday BR, Poc TE, Webb CE, Porter RS, Gal P, et al. A multicenter evaluation of variables affecting the predictability of creatinine clearance. Am J Clin Pathol 1982; 78(6): 832-8.
Gates GF. Glomerular filtration rate: estimation from fractional renal accumulation of 99mTc DTPA (stannous). AJRAm J Roentgenol 1982; 138(3): 565-70.
Itoh K. Comparison of methods for determination of glomerular filtration rate: 99mTc DTPA renography, predicted creatinine clearance method and plasma sample method. Ann Nucl Med 2003; 17(7): 561-5.
Delpassand ES, Homayoon K, Madden T, Mathai M, Podoloff DA. Determination of glomerular filtration rate using a dual-detector gamma camera and the geometric mean of renal activity: correlation with the 99mTc DTPA plasma clearance method. Clin Nucl Med 2000; 25(4):258-62.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 The ASEAN Journal of Radiology
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Disclosure Forms and Copyright Agreements
All authors listed on the manuscript must complete both the electronic copyright agreement. (in the case of acceptance)