The Outcome of Craniospinal Irradiation in Supine Position at Siriraj Hospital: Preliminary Results
Keywords:
Craniospinal irradiation, supine positionAbstract
Objective: To study the outcome of craniospinal irradiation (CSI) in supine position in aspect of treatment control and acute treatment toxicity.
Materials and Methods: The medical records of all patients treated with CSI in supine position between July 2007 and December 2008 at Division of Radiation Oncology. Department of Radiology, Siriraj Hospital were retrospectively reviewed.
Results: Twenty patients were identified with 13 (65%) showed complete response at median follow-up 23.5 months. No one developed intracranial. spinal or distant failure. No disease failure occurred at craniospina or spinalspinal junction from CSI in supine position. Grade 3-4 leucopenia and neutropenia were found in 13 (65%) and 11 (55%) patients respectively.
Conclusion: Supine position can be an alternative technique for CSI. Disease control is acceptable with some Grade 3-4 hematologic toxicity.
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