• Makumkrong POSHYACHINDA Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine, Chulalongkorn University
  • Tawatchai CHAIWATANARAT Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine, Chulalongkorn University


Bone mineral density, Bone mass, Bone densitometer, Dual energy x-ray absorbtiometer


Bone mineral density (BMD) of anterior and lateral lumbar spine and femoral neck were studied in 301 normal healthy subjects (205 women and 96 men; age range, 20-84 years) utilizing dual energy x-ray absorptiometer (DEXA). In normal women, bone mass was increased with age and peaked around age 35 at all three scanning sites. Bone diminution began about the age of 40 and the loss was accelerated after age 50. The average rate of loss upto age 75 was 0.8% per year at all sites. In normal men, the pattern of bone diminution with age was different from women. Bone diminution from vertebrae and femoral neck began in young adulthood and were linear. The rate of decrease in BMD was two-thirds of that in women for femoral neck but was only one-fifth of that in women for anterior lumbar spine. Mean BMD in women was less than men at all three scanning sites.


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Peck WA, Riggs BL and Bell NH. The biology of bonc. In Physician's resource manual on osteoporosis. A decision-making guide. Published by National Osteoporosis Foundation. USA 1987, P. 2-5.

Stevenson JC and MI Whitehead. Post menopausal osteoporosis. Br. Med J 1982; 285: 585-588.

Nordin BEC, Horsman A, Crilly RG, Marshall DH and Sympson M. Treatment of spinal osteoporosis in postmenopausal women. Br. Med J 1980; 280: 451-454.

Spector TD, Cooper C and Fenton Lewis. Trends in admission for hip fracture 1968-1985 in the U.K. Brit Med J 1990; 300: 1173-1174.

WHO Technical Report Series: 843, WHO Study group on assessment of fracture risk and its application to screening for postmenopausal osteoporosis, Rome, 22-25 June 1992.

Wasnich RD. Bone mass measurements in diagnosis and assessment of therapy. Amer J Medicine 1991; 91 (suppl 5B): 54s-58s.

Siberstein EB. Update on the diagnosis and therapy of osteoporosis. Nucl Med Annual. New York. Raven Press 1988; 209-243.

Fogelman I. Bone scanning in osteoporosis: The role of radionuclide bone scan and photon absorptiometry. Nucl Med Annual. New York. Raven Press 1990; 1-37.

Genant HK, Faulkner KG and Gluer CC. Mesurement of bone mineral density: Current status. Proceedings of a Symposium on osteo- porosis. Am J Med 1991; 91 (5B): 49-53.

Svendsen OL, Marslew U, Hassagar C and Christiansen C. Measurement of bone mineral density of the proximal femur by two commer- cially available dual energy x-ray absorptiometric system. Eur J Nucl Med 1992; 19: 41-46.

Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltabv N. Perspective. The diagnosis of osteoporosis. J Bone Min Res 1994; 9 (3): 1137-1141.

Chompootweep S, Tankeyoon M, Yamarat K, Pumsuwan P, Dusitsin N. The menopausal age and climateric complaints in Thai women in Bangkok. Maturitas 1993; 17: 63-71.

Hall ML, Heavens J, Cullum ID, Ell PJ. The range of bone density in normal British women. Brit J Radiol 1990; 63: 266-269.

Riggs BL, Wahner HW, Dunn WL, Mazess RB, Offord KP, Melton LJ. Differential changes in bone mineral density of the appendicular and axial skeleton with aging. Relationship to spinal osteoporosis. J Clin Invest 1981; 67: 328-335.

Riggs BL, Wahner HW, Melton LJ III, Richelson LS, Judd HL, Offord KP. Rates of bone loss in the axial and appendicular skeletons of women : evidence of substantial vertebral bone loss prior to menopause. J Clin Invest 1986; 77: 1487-1491.

Krolner B, Pors Nielsen S. Bone mineral content of lumbar spine in normal and osteoporotic women cross sectional and longitudinal studies. Clin Sci 1982; 62: 326-329.

Genant HK, Cann CE, Ettinger B, Gordon GS. Quantitative computed tomography of vertebral spongiosa a sensitive method for detecting early bone loss after öophorectomy. Ann Intern Med 1982; 97: 699-705.

Riggs BL, Wahner HW, Seeman E, et al. Changes in bone mineral density of the proximal femur and spine with aging. Differences between the postmenopausal and senile osteoporosis syndromes. J Clin Invest 1982; 70: 716-723.

Meier DE, Orwoll ES, Jones JM. Marked disparity between trabecular and cortical bone loss with age in healthy men measurement by vertebral computed tomography and radial photon absorp- tiometry. Ann Intern Med 1984; 101: 605-612.




How to Cite

POSHYACHINDA M, CHAIWATANARAT T. ASSESSMENT OF BONE MINERAL DENSITY IN NORMAL THAIS. ASEAN J Radiol [Internet]. 2023 Mar. 31 [cited 2024 Jun. 13];2(1):1-12. Available from:



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