NON-OSSEOUS UPTAKES OF TC-99M PHOSPHONATE DURING THREE PHASE BONE SCAN
Keywords:
Bone scan, Non-osseous UptakeAbstract
Objective : The purpose of this study was to visualize non-osseous uptakes of bone scanning agent.
Methods : Amongst 51 patients (M21, F30) of age range 8-80 years having three phase bone scan at NNC, Rangpur during January 2000 to January 2002, we looked for non-osseous uptake.
Results : Twenty four patients had non-osseous uptakes of 99 metastable technetium methylenediphosphonate (99m Tc MDP), 19 in kidneys (14 in right, 4 in left kidney, one patient showing hold-up in both kidneys), 3 in breasts (2 in left, 1 in right breast), and two patients had lung uptakes. Renal, pulmonary and mammary uptakes of this series are not always due to malignant process, however, one patient had cisplatin nephrotoxicity.
Conclusion : Non-osseous uptake of bone-seeking radiopharmaceutical is quite common (24/51 i.e. about 48% in this series), however, most of these may be nonmalignant.
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Furnival CM, Blumgart LH, Citrin DL et al. Serial scinatiscanning in breast cancer The indications and prognostic value, Clin Oncol 1980 : 6 : 25
Burnett KR et al. Uptake of osteotropic radionuclides in the breast. Semin Nucl Med 1984: 14: 48-49.
McDougal I R, Pistenma DA, Concentration of 99m Tc diphosphonate in breast tissue. Radiology 112 : 655-657, 1974
Holmes R A, Manoli R S, Isitman A T Tc-99m labelled phosphates as an indicator of breast pathology J Nucl Med 16: 536, 1975
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