CRONKHITE-CANADA SYNDROME - REPORT OF A CASE AND LITERATURE REVIEW

Authors

  • Abhasnee SOBHONSLIDSUK Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Surat KOMINDR Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Patchrin PEKANAN Department of Radiology. Faculty of Medicine, Ramathibodi Hospital, Mahidol University,
  • Siripen PUAVILAI Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Sukhum BUNYARATVEJ Department of Pathology. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Kaseansom VIRANUVATTI Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Pravit LERDVERASIRIKUL Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Sucha KURATHRONG Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University

Abstract

This article reported a case of Cronkhite—Canada syndrome. The patient was 56 years old, presented with diarrhea, anorexia and weight loss. On physical examination, there were glossitis, hair loss, onychomadesis, palmar and sole hyperpigmentation. Laboratory revealed evidence of nutritional deficiencies. Radiological and panendoscopic studies showed gastrointestinal polyposis in the stomach, duodenum and colon. Biopsies of all polyps revealed hyperplastic polyps with retention cystic gland dilatation. After 6" month of proper neutritional support, his condition improved strikingly and ectodermal change disappeared. Colonic polyposis showed almost complete regression and partial regression of the gastric polyposis. This case is not reported for its rarity. Emphasis is made for early recognition with prompt and appropirate therapy to avoid its potentially high morbidity and mortality.

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References

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Published

2023-04-11

How to Cite

1.
SOBHONSLIDSUK A, KOMINDR S, PEKANAN P, PUAVILAI S, BUNYARATVEJ S, VIRANUVATTI K, et al. CRONKHITE-CANADA SYNDROME - REPORT OF A CASE AND LITERATURE REVIEW. ASEAN J Radiol [Internet]. 2023 Apr. 11 [cited 2025 Jan. 31];5(3):289-95. Available from: https://asean-journal-radiology.org/index.php/ajr/article/view/502

Issue

Vol. 5 No. 3 (1999): September-December

Section

Original Article

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