CRONKHITE-CANADA SYNDROME - REPORT OF A CASE AND LITERATURE REVIEW

Authors

  • Abhasnee SOBHONSLIDSUK Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Surat KOMINDR Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Patchrin PEKANAN Department of Radiology. Faculty of Medicine, Ramathibodi Hospital, Mahidol University,
  • Siripen PUAVILAI Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Sukhum BUNYARATVEJ Department of Pathology. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Kaseansom VIRANUVATTI Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Pravit LERDVERASIRIKUL Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Sucha KURATHRONG Department of Medicine. Faculty of Medicine, Ramathibodi Hospital, Mahidol University

Abstract

This article reported a case of Cronkhite—Canada syndrome. The patient was 56 years old, presented with diarrhea, anorexia and weight loss. On physical examination, there were glossitis, hair loss, onychomadesis, palmar and sole hyperpigmentation. Laboratory revealed evidence of nutritional deficiencies. Radiological and panendoscopic studies showed gastrointestinal polyposis in the stomach, duodenum and colon. Biopsies of all polyps revealed hyperplastic polyps with retention cystic gland dilatation. After 6" month of proper neutritional support, his condition improved strikingly and ectodermal change disappeared. Colonic polyposis showed almost complete regression and partial regression of the gastric polyposis. This case is not reported for its rarity. Emphasis is made for early recognition with prompt and appropirate therapy to avoid its potentially high morbidity and mortality.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Erno S. Daniel et al. The CronkhiteCanada syndrome. An analysis of clinical and pathologic features and therapy in 55 Patients. Medicine (Baltimore) 1982;6: 293.

Cronkhite, L.W., and Canada, WJ. Generalized gastrointestinal polyposis. An unusual syndrome of polyposis, pigmentation, alopecia and onychotophia. N Engl J Med. 1955;252:1011. 3

. Finan MC,Ray MK. Gastrointestinal Polyposis Syndrome. Dermatol Clin 1989;7(3): 419-34.

Goto A. Cronkhite Canada syndrome: epidermiology study of 110 cases reported in Japan. Nippon Geka Hokan 1995:64 (1):3-14.

Vikit Viranuvatti, Chiamchit Damrongsak, Termchai Chainuvatti, Boon Vanasin, Chintana Chadrcharoensin. Cronkhite Canada syndrome: report of acase with spontaneous recovery. J. Med. Ass. Thailand 1981;64(5):261-6.

Allen P. Burke, Leslie H. Sobin. The Pathology of Cronkhite-Canada Polyps. A comparison to Juvenile Polyposis. The American Journal of Surgical Pathology 1989;13(11):940-6.

Steven H. Itzkowitz, Young S. Kim. Colonic polyps and polyposis syndromes. Gastrointestinal and Liver Disease 6" edition: 1865-1905.

Malhortra R., Sheffield A. CronkhiteCanada yndrome associated with colon carcinoma and adenomatous changes in CC polyps. Am J Gastroentero! 1988;83(7): 772-6.

Kennedy J.A., and Hirson C.: A transient syndrome with Peutz-Jeghers features and ectodermal change. Proc. Roy. Soc. Med. 1961,54:234.

Russell DM, Bhathal PS, St John DJ. Complete remission in Cronkhite-Canada syndrome. Gastroenterology 1983 Jul; 85 (1):180-5.

Downloads

Published

2023-04-11

How to Cite

1.
SOBHONSLIDSUK A, KOMINDR S, PEKANAN P, PUAVILAI S, BUNYARATVEJ S, VIRANUVATTI K, et al. CRONKHITE-CANADA SYNDROME - REPORT OF A CASE AND LITERATURE REVIEW. ASEAN J Radiol [Internet]. 2023 Apr. 11 [cited 2025 Jan. 31];5(3):289-95. Available from: https://asean-journal-radiology.org/index.php/ajr/article/view/502

Issue

Vol. 5 No. 3 (1999): September-December

Section

Original Article

License

Copyright (c) 2023 The ASEAN Journal of Radiology

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Disclosure Forms and Copyright Agreements
All authors listed on the manuscript must complete both the electronic copyright agreement. (in the case of acceptance)

Most read articles by the same author(s)

<< < 3 4 5 6 7 8