THE MEASUREMENT OF DOSE TO THE LENS FROM PROPHYLACTIC CRANIAL [IRRADIATION IN ACUTE LYMPHOBLASTIC LEUKEMIA

Authors

  • Nan SUNTORNPONG Department of Radiology, Siriraj Faculty of Medicine, Mahidol University
  • Porntip THAMWINICHAI Department of Radiology, Siriraj Faculty of Medicine, Mahidol University
  • Apinya NANGKALA Department of Radiology, Siriraj Faculty of Medicine, Mahidol University

Abstract

This study was performed to measure the radiation dose to lens by thermoluminescent dosimetry in the children with acute lymphoblastic leukemia treated by prophylactic cranial irradiation. Ten patients treated at Division of Radiation Oncology, Department of Radiology, Siriraj Faculty of Medicine from January 1999 to May 1999 were included. The dose measured by 5 degrees posterior angle of the opposed lateral beams was less than 2 % decreased compared to that without angling beams. The mean calculated doses to the lens in this study were in the range of 135 — 263 cGy for the whole course of treatment. The clinical effect on this organ need to be further followed -up.

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References

Tumor Registry. Siriraj Cancer Center. Statistical Report 1998. Faculty of Medicine Siriraj Hospital.

Waber DP, Tarbell NJ. Toxicity of CNS prophylaxis for childhood leukemia. Oncology (Huntingt) 1997;11:259-64.

Birkebaek NH, Fisker S, Clausen N et al. Growth and endocrinological disorders up to 21 years after treatment for acute lymphoblastic leukemia in childhood. Med Pedistr Oncol 1998;30:351-56.

Halberg FE, Kramer JH, Moore IM et al. Prophylactic cranial irradiation dose effects on late cognitive function children treated for acute lymphoblastic leukemia. IntJ Radiat Oncol Biol Phys 1992;22:13-6.

Moss WT. The Orbit. In: Moss WT, Cox JD, eds,6th ed. Radiation Oncology. Rationale, Technique, Results. C.V. Mosby, St.Louise 1989:173-83.

Kline RW, Gillin MT, Kun LE. Cranial irradiation in acute leukemia: dose estimate in the lens. Int J Radiat Oncol Biol Phys 1979;5:117-21.

Pakisch B, Stucklschweiger G, poier E. et al. Reduction of the dose to the lens in prophylactic cranial irradiation: A comparison of three different treatment techniques and two different beam qualities. Int J Radiat Oncol Biol Phys 1992;23:183-88.

Woo SY, Donaldson SS, Heck RJ. Minimizing and measuring lens dose when giving cranial radiation. Radiother Oncol 1989;16,183-88.

Gordon KB, Char DH, Sagerman RH. Late effects of radiation on the eye and ocular adnexa. IntJ Radiat oncol biol phys 1995; 31:1123-40

Merriam GR, Focht EF. A clinical study of radiation cataracts and the relationship to dose. Am J Roentgenol 1957;77,759-85.

Fishman ML, Bean SC, Cogan DG. Optic atrophy following prophylactic chemotherapy and cranial radiation for acute lymphocytic leukemia. Am J Ophthalmol 1976;82:571-6.

Uberall MA, Hertzberg H, Meier W et al. Visual -evoked potentials in long-term survivors of acute lymphoblastic leukemia in childhood. The German Late Effects Working Group. Neuropediatrics 1996; 27:194-6.

Hall E. Cataractogenesis. In: Hall EJ, ed, 4th ed. Radiobiology for the Radiologists J.B. Lippincott, Philadelphia, 1994 323- 47,

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Published

2023-04-11

How to Cite

1.
SUNTORNPONG N, THAMWINICHAI P, NANGKALA A. THE MEASUREMENT OF DOSE TO THE LENS FROM PROPHYLACTIC CRANIAL [IRRADIATION IN ACUTE LYMPHOBLASTIC LEUKEMIA. ASEAN J Radiol [Internet]. 2023 Apr. 11 [cited 2025 Feb. 22];5(3):245-8. Available from: https://asean-journal-radiology.org/index.php/ajr/article/view/493

Issue

Vol. 5 No. 3 (1999): September-December

Section

Original Article

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