THE ADVANTAGE OF DOUBLE PHASE99™ TC-MIBI SCINTIGRAPHY OVER DUAL-TRACER SUBTRACTION METHOD IN TERTIARY HYPERPARATHYROIDISM WITH SICK EUTHYROID SYNDROME

Authors

  • Supatporn TEPMONGKOL Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine, Chulalongkorn University
  • Kanaungnit KINGPETCH Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine, Chulalongkorn University
  • Supot BOONVISUT Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine, Chulalongkorn University

Keywords:

Sick euthyroid syndrome, parathyroid scintigraphy, tertiary hyperparathyroidism, chronic renal failure

Abstract

Pre-operative parathyroid scintigraphy can be performed by 2 major means, dualtracer subtraction method and double-phase 99mTc-MIBI method. Although, the sensitivities of both techniques are similar, many types of patient cannot be studied using the former one. Here is a case of tertiary hyperparathyroidism in chronic renal failure who has co-existing sick euthyroid syndrome causing no uptake of 99mTc-pertechnetate. The double-phase 99mTc-MIBI technique in this type of patient is proven to be more useful.

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References

Lundgren E, Gillott A, Weiseman J, Beck J. The role of preoperative localization in primary hyperparathyroidism. Am Surg 1995;61:393-6.

Chen CC, Holder LE, Scovill WA, Tehan AM, Gann DS. Comparison of parathyroid imaging with technetium-99m pertechnetate/sestamibi subtraction, double-phase technetium-99m-sestamibi and technetium-99m-sestamibi SPECT. J Nucl Med 1997;38(6):843-9.

John T, Potts JR. Diseases of the parathy roid gland and other hyper- and hypocal cemic disorder. In: Wilson JD, Braunwald E, Isselbacher KJ, et al, eds. Principles of internal medicine. 12™ed. New York: McGraw-Hil, 1991: 1902-21.

Mallette LE. The functional and pathologic spectrum of parathyroid abnormalities in hyperparathyroidism. In: Bilezikian JP, Marcus R, Levine MA, eds. The parathyroids:Basic and clinical concepts. Ist ed. New York: Raven Press,1994: 423-55.

Mazzeo S, Caramella D, Lencioni R, et al. Comparison among sonography, doubletracer subtraction scintigraphy, and doublephase scintigraphy in the detection of parathyroid lesions. Am J Roentgenol 1996; 166(6):1465-70.

Neumann DR, Esselstyn CB Jr, Go RT, et al. Comparison of double-phase 99mTcsestamibi with 123]-99mTc-sestamibi subtraction SPECT in hyperparathyroid ism. Am J Roentgenol 1997;169(6):1671-4.

Krubsack AJ, Wilson SD, Lawson TL, et al. Prospective comparison of radionu clide, computed tomographic, sonographic, and magnetic resonance localiza tion of parathyroid tumors. Surgery 1989; 106(4):639-46.

Krause MW, Hedenger CE. Pathologic study of parathyroid glands in tertiary hypertparat- hyroidism. Hum Pathol 1985; 16(8):772-84.

Kilgo MS, Pirsch JD, Warner TF, Starling JR. Tertiary hyperparathyroidism after renal transplantation: surgical strategy. Surgery 1998; 124(4):677-83.

Chesser AM, Carroll MC, Lightowler C, et al. Technetium-99m methoxy isobutyl isonitrile (MIBI) imaging of the parathy roid glands in patients with renal failure. Nephrol Dial Transplant 1997;12(1):97-100.

Chen EM, Mishkin FS. Parathyroid hyper plasia may be missed by double-phase Tc- 99m sestamibi scintigraphy alone. Clin Nucl Med 1997;22(4):222-6.

Wartofsky L, Ingbar SH. Disease of the thyroid. In: Wilson JD, Braunwald E, Isselbacher KJ, et al, eds. Principles of internal medicine. 12th ed. New York: McGraw-Hil, 1991:1692-1712.

Mettler FA Jr., Guiberteau MJ. Thyroid and parathyroid. In: Essentials of Nuclear Medicine (ed3). Philadelphia, W.B. Saunders, 1991:75-94.

Civelek AC, Durski K, Shafique I, et al. Failure of perchlorate to inhibit Tc-99m isonitrile binding by the thyroid during myocardial perfusion studies. Clin Nucl Med 1989:16(5):358-61.

Vattimo A, Bertelli P, Burroni L. Effective visualization of suppressed thyroid tissue by means of baseline 99mTc-methoxyisobutyl isonitrile in comparison with 99mTc-pertechnetate scintigraphy after TSH stimulation. J Nucl Biol Med 1992:36 (4):315-8.

Chiu ML, Kronauge JF, Piwnica-Worms D. Effect of mitochondrial and plasma membrane potentials on accumulation of hexakis (2-methoxyisobutylisonitrile) technetium (I) in cultured mouse fibroblasts. J Nucl Med 1990;31(10):1646-53.

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Published

2023-04-10

How to Cite

1.
TEPMONGKOL S, KINGPETCH K, BOONVISUT S. THE ADVANTAGE OF DOUBLE PHASE99™ TC-MIBI SCINTIGRAPHY OVER DUAL-TRACER SUBTRACTION METHOD IN TERTIARY HYPERPARATHYROIDISM WITH SICK EUTHYROID SYNDROME. ASEAN J Radiol [Internet]. 2023 Apr. 10 [cited 2024 Jul. 7];5(2):199-204. Available from: https://asean-journal-radiology.org/index.php/ajr/article/view/488

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