ADENOCARCINOMA OF THE CERVICAL CANCER : RADIATION TREATMENT IN SIRIRAJ HOSPITAL 1993-1995
Abstract
Objective : To evaluate the incidence and the results of the radiation treatment in adenocarcinoma and adenosquamous cell carcinoma of the cervical cancer.
Study design : A retrospective review of 125 patients with adenocarcinoma and adenosquamous cell carcinoma of the cervical cancer who had the primary radiation treatment in between 1993 - 1995.
Result : After the completion the radiation treatment, there were 35 patients (28.0 %) who had residual disease. The median follow up time was 43.5 months, 61 patients (48.8 %) still had no evidence of disease, 16 patients (12.8%) had local recurrence and 23 patients (18.4 %) developed distance metastasis.
Conclusion : The radiation treatment is the primary treatment for stage II and stage III adenocarcinoma of the cervical cancer. The total abdominal hysterectomy is recommended after the completion of radiation treatment to improve the local control. For stage I diseases, radiation treatment can be used as the primary treatment especially for bulky lesions. The adjuvant hysterectomy is also recommended to improve local control. The concurrent chemo-radiation is suggested for locally advanced lesions to improve the tumor control. The adjuvant chemotherapy should be benefit for the residual tumor, which is not suitable for surgery and also recommended for improving the survival in lymph nodes positive patients. Any how, a further study should be done.
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