A HUGE MEDIASTINAL GERM CELL TUMOR

Authors

  • Panpen UTTAMAKUL Department of Radiology, Prince of Songkla University Hospital
  • Patchrin PEKANAN Department of Radiology, Ramathobodi Hospital
  • Mana ROJANAVUTHINON Department of Pathology, Ramathibodi Hospital
  • Pakorn JIARAKONOMUN Department of Radiology, Ramathobodi Hospital

Abstract

A case of a huge mediastinal endodermal sinus tumor was shown in a 22-year- old male who presented with chronic cough and dyspnea. The mediastinal mass extends from right anterior mediastinum to the right posterior mediastinum. The tumor was a mixture of solid and cystic tissue. The airway was severely compressed. The sternum was destroyed and the anterior chest wall was invaded. The right pleural effusion was massive and multiple pleural nodules were found. The alpha feto-protein was markedly elevated and the beta HCG was zero. The patient passed away due to profound shock immediately after the procedure of intercostal drainage.

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References

Fraser, Pare, Pare, Fraser, Genereux. Diagno- sis of diseases of the chest. 3rd ed. Philadelphia: W.B. Saunders Company, 1991:2835-6.

Luna MA, Valenzuela - Tamariz J. Germ-cell tumors of the mediastinum; postmortem findings. Am J Clin Pathol 1976;65:450.

Knapp RH, Hurt RD, Payne WS, et al. Malig- nant germ cell tumors of the mediastinum. J Thorac Cardiovasc Surg 1985;82:9.

Wychulis AR, Payne WS, Clagett OT, et al. Surgical treatment of mediastinal tumors. A 40- year experience. J Thorac Cardiovasc Surg 1971;62:379.

Benjamin SP, McCormack LJ, Effler DB, et al. Critical review- Primary tumors of the me- diastinum. Chest 1972;62:297.

Yurick BS, Ottoman RE. Primary mediastinum choriocarcinoma. Radiology 1960;75:901.

Steinmetz WH, Hays RA. Primary seminoma of the mediastinum. Report of a case with an unusual site of metastasis and review of the literature. Am J Roentgenol 1961;86:669.

Wenger ME, Dines DE, Ahmann DL, et al. Primary mediastinal choriocarcinoma. Mayo Clin Proc 1968;43:570.

Aliotta PJ, Castillo J, Englander LS, et al. Primary mediastinal germ cell tumors. Histo- logic patterns of treatment failures at autopsy. Cancer 1988;62:982.

Sogge MR, McDonald SD, Cofard PB. The malignant potential of the dysgenetic germ cell in Klinefelter's syndrome. Am Med 1979;66:515.

Lachman MF, Kim K, Koo B-C. Mediastinal teratoma associated with Klinefelter's syn- drome. Arch Pathol Lab Med 1980;110:1067.

McNell MM, Leong AS-Y, Sage RE. Primary mediastinal embryonal carcinoma in association with Klinefelter's syndrome. Cancer 1981;47:343.

Richardson RL, Schoumacher BS, Fer MF, et al. The unrecognized extragonadal germ cell cancer syndrome. Ann Intern Med 1981;94:181.

Truong LD, Harris L, Mattioli C, et al. Endo- dermal sinus tumor of the mediastinum. A report of seven cases and review of the literature. Cancer 1986;58:730.

Mukai K, Adams WR. Yolk sac tumor of the anterior mediastinum. Case report with light and electron microscopic examination and immuno- histochemical study of alpha-fetoprotein. Am J Surg Pathol 1979;3:77.

Kuzur ME, Cobleigh MA, Greco A, et al. Endodermal sinus tumor of the mediastinum. Cancer 1982;50:776.

Rusch VW, Logothetis C, Samuels M. Endo- dermal sinus tumor of the mediastinum. Report of apparent cure in two patients with extensive disease. Chest 1984;86:745.

Sham JST, Fu KH, Chiu CSW, et al. Expe- rience with the management of primary endo- dermal sinus tumor of the mediastinum. Cancer 1989;64:756.

Wallach J. Interpretation of diagnostic tests: A synopsis of laboratory medicine. 5th ed. Boston; Little, Brown and Company, 1992:539.

Haaga JR, Lanzieri CF, Sartoris DJ, Zerhouni EA. Computed tomography and magnetic reso- nance imaging of the whole body. 3rd ed. St. Louis; Mosby, 1994:753.

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Published

2023-04-06

How to Cite

1.
UTTAMAKUL P, PEKANAN P, ROJANAVUTHINON M, JIARAKONOMUN P. A HUGE MEDIASTINAL GERM CELL TUMOR. ASEAN J Radiol [Internet]. 2023 Apr. 6 [cited 2024 Nov. 22];3(2):147-52. Available from: https://asean-journal-radiology.org/index.php/ajr/article/view/376

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