Successful Diagnostic and Complication Rate in CT Guided Lung Biopsy: Comparison of Core Needle Biopsy and Fine Needle Aspiration Biopsy in Different Size Pulmonary lesions
Abstract
Objective: The aim of the study was to compare successful diagnostic and complication rate of core needle biopsy (CNB) with those of fine needle aspiration biopsy (FNAB) performed on pulmonary lesions of different sizes.
Materials and Methods: We retrospectively reviewed results and complications of 156 consecutive percutaneous CT guided biopsy of pulmonary lesions obtaining in January 2007 to July 2009. performed with either CNB (Semiautomatic cutting biopsy device 18 G) or FNAB (Spinal needle 20 G). The patients who performed with both CNB and FNAB were excluded. Fifty-four Core needle biopsies and 102 Fine needle aspiration biopsies were recorded. The successful diagnostic and complication rates of each method were compared in lesion less than 1 cm, equal 1 cm to less than 3 cm and greater than 3 cm in AP diameter.
Results: The overall successful diagnostic rate of our procedure was 76.3%. There was no statistically significant difference (p<.05) between successful diagnostic rate of CNB and FNAB in every size of pulmonary lesion (40.0% Vs 54.5% in lesion less than 1 cm, 78.6% Vs 69.7% in lesion equal 1 cm to less than 3 cm, 90.5% Vs 88.0% in lesion greater than 3 cm) as well as complication rate of CNB and FNAB in every size of pulmonary lesion (40% vs 36.4% in lesion less than 1 cm. 35.7%Vs28.8% in lesion equal 1 cm to less than 3 cm, 24.0% Vs 39.1% in lesion greater than 3 cm). But. there was statistically significant difference (p<.05) between successful diagnostic rate of lesion less than 1 cm (54.5%) and lesion greater than 3 cm (88.0%) when biopsy was performed by FNAB, between successful diagnostic rate of lesion less than 1 cm (40.0%), lesion equal to 1 cm to less than 3 cm (78.6%) and lesion greater than 3 cm (90.5%) when biopsy was performed by CNB. There was no statistically significant difference (p<.05) between complication rate in every size of lesion when biopsy was performed by either CNB or FNAB.
Summary: CT guide lung biopsy is significantly less accurate for small pulmonary lesion (less than 1 cm in AP diameter) than for larger pulmonary lesion. There was no significant difference of successful diagnostic and complication rate when CT guide lung biopsy was performed by either CNB or FNAB.
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