UTERINE FIBROID EMBOLIZATION(UAE): CHANGE IN VOLUME OF FIBROID AND THE UTERUS
Abstract
Purpose: For evaluation the effectiveness of bilateral uterine arterial embolization, (UAE) in the treatment of fibroids, in aspect of changes in volume of fibroid and the uterus.
Material and Method: Retrospective study of pre and post UAE MRI in 8 Thai women, mean age 36 years who were to undergo bilateral UAE of uterine fibroids. from January, 2006-January, 2008. The follow up MRI was 15d, Imonth, 3months(3 pts), 6months (2pts) and 2 yrs(1pt). Bilateral UAE was performed by injecting 500-700 micron polyvinyl! alcohol (PVA) or 700-900 micron Beadblock. Two radiologists interprete MRI by consensus. The volume of fibroid and the uterus was calculated by the formula:lengthxdepthx width x 0.523 The signal intensity change in MRI after UAE was observed.
Result: Technical results Bilateral embolization of uterine arteries was accomplished in all patients( 100%). Patients had multiple fibroids (range 1-6 lesions). 26 fibroids were noted. The volume of fibroids varied from 3.6-512.4 cm3(mean=94.1 cm3). The mean volume reduction of fibroids after bilateral UAE was 36.75%. The mean volume reduction of intramural lesions was 44.54%. The mean volume reduction of subserosal and submucosal lesions were 28% and 25% respectively. No major complication, no mortality was occurred.
Conclusion: Significant volume reduction of fibroid after bilateral uterine artery embolization for treatment of fibroid with good clinical outcomes.
Downloads
Metrics
References
Cramer SF, Patel A. The frequency of uterine leiomyomas. Am J Clin Pathol 1990; 94: 435-438.
Baird DD, Dunson DB, Hill Mc et al. High cumulative incidence of uterine leiomyoma in black and white women: Ultrasound evidence. Obset Gynecol 2003: 188; 100-107.
Wilcox LS, Koonin LM, Pobras R, et al. Hysterectomy in the united states, 1998-1990. Obstet Gynecol 1994; 83: 549-555.
Burn p. McCall JM, Chinn r.et al. Embolization of uterine fibroids. Br J Radiol 1999; 72: 159-161
Jha RC. Ascher SM, Imaoka I et al. Syumptomatic fibroleriomyomata: MR imagin of the uterus before and after uterine embolization. Radiology 2000; 217: 228-231.
Tetsuya Katsumori, Kazuhiro Nakajima, et al Is large fibroid a high risk factor for uterine artery embolization. AJR; 2003: 181: 1309- 1314
Nandita M. deSonza et al. Uterine arterial embolization for leiomyomas: Perfusion and volume change at MR imaging and relation to clinical outcome. Radiology: Feb 2002: 365- 373
Casey R, Rogers PA, Vollenhoven BJ. An immunohistochemical analysis of fibroid vasculature. Hum Reprod 2000; 15: 1469- 1475
Pelage JP, Le Dref O, Soyer P. et al. Fibroidrelated menorrhagia: treatment with superselective embolization of the uterine arteries and midterm follow up. Radilogy 200; 215: 428- 431
James B. Spies, Jean -Pierre Pelage. Uterine artery embolization and synecologic embolotherapy 2004: 6-7, 41-45
Walker WJ, Pelage JP. Uterine artery embolization for symptomatic fibroids: clinical results in 400 women with imaging follow up. BJOG 2002; 109: 1262-1272
Worthington-Kirsch RL, Popky GL, Hutchins FL Jr. Uteine arterial embolizatiion for the management of leiomyomas, quality of life assessment and clinical response. Radiology 1998: 208: 625-629
Molly T., Johanna L., et al. Cost-effectiveness of uterine artery embolization and hysterectomy for uterine fibroids. Radiology 2004; 230: 207-212
Haney AF. Clinical decision making regarding leiomyomata: what we need in the next millennium. Environ Health Perspect 2000; 108: 835-839
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 The ASEAN Journal of Radiology
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Disclosure Forms and Copyright Agreements
All authors listed on the manuscript must complete both the electronic copyright agreement. (in the case of acceptance)