DEEP FIBROMATOSIS (DESMOID TUMOR) IN THE TRUNK AND ABDOMEN: CT/MRI AND PATHOLOGICAL FINDINGS

Authors

  • Wichchuda YAMRUBBOON Department of Radiology
  • Sith PHONGKITKARUN Department of Radiology
  • Suphaneewan JAOVISIDHA Department of Radiology
  • Vorachai SIRIKULCHAYANONTA Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Jiemjit TAPANEEYAKORN Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University

Abstract

Objective: To describe imaging findings (Computerized Tomography [CT]/ Magnetic Resonance Imaging [MRI]) correlated with pathological findings, of the deep fibromatosis (desmoid tumor) in the trunk and abdomen.

Material and methods: We retrospectively reviewed such cases in Ramathibodi hospital from January 2001 to December 2005, who had CT/MRI imaging along with pathological slices available.

Results: Seven cases were enrolled in the study ; four of 7 had CT examinations and the other 3 had MR imaging. The locations were extra-abdominal (n=4), intra-abdominal (n=2), and abdominal-wall desmoid tumor (n=1). The margins were well-defined (n=3), partially well-defined (n=3), and ill-defined (n=1). On CT, they were iso- or hypodense. On MRI, although the lesions were iso- to hypointense-T1 and heterogeneously hyperintense-T2 ; there were ill-defined areas of hypointensity in both T1 and T2-weigthed images that was the signal of fibrous tissue. Most lesions showed moderate to strong enhancement after IV contrast injection. Histology showed area of spindle cells in dense collagen fiber, with small & large slitlike vessels. There was no nuclear atypia in majority.

Conclusion: Deep fibromatosis (desmoid tumor) has nonspecific CT findings. In MRI, identifying area of hypointensity on both T1WI and T2WI, with varying degree of enhancement after Gadolinium injection, helps in the diagnosis of the nature of fibrous-origin tumors.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Kempson R, Fletcher C, Evans H, Hendrickson M, Sibley R. Fibrous and myofibroblastic tumors In: Rosai J, Sobin L, editors. Atlas of Tumor Pathology. Washington, DC. Armed Forces Institute of Pathology 2001 ; 23-104.

Enzinger F, Weiss S. General consideration. In: Gay S, editor. Soft tissue tumors. 3 ed. St Louis: Mosby 1995 ; 1-15.

Lektrakul N, Chanchairujira K. Imaging of soft tissue tumors. In: Asavamongkolkul A, editor. The Management of Soft Tissue Tumors. Bangkok: P.A.Living 2004 ; 25-58.

Armstrong S, Watt I. Imaging of soft tissue tumors. Curr Opin Radiology. 1992; 75: 39- 44.

Sim F, Frassica F, Frassica D. Soft-tissue tumors: diagnosis, evaluation, and management. J Am Acad Orthop Surg. 1994; 2: 202-11.

Kransdorf M, Murphey M. Radiologic evaluation of soft tissue masses. AJR. 2000; 175 :575-87.

Richard P, JR John E. Radiological evaluation of soft tissue tumor. In: Gay S, editor. Soft tissue tumor. 3 ed. St Louise: Mosby 1995 ; 39-118.

Hartman T, Berquist T, Fetsch J. MR imaging of extra-abdominal desmoids: differentiation from other neoplams. AJR. 1992;158: 581-5.

Shields C, Winter D, Kirwan W, Redmond H. Desmoid tumors. EurJ Surg Oncol. 2001;27: 701-6.

Kulaylat M, Karakousis C, Keaney C, McCorvey D, Bem J, Ambrus S J, et al. Desmoid tumor: a pleomorphic lesion. EurJ Surg Oncol. 1999; 25: 487-97.

Clark S, Neale K, Landgrebe J, Phillips R. Desmoid tumors complicating familial adenomatous polyposis. BrJ Surg. 1999; 86: 1185-9.

Knudsen A, Bulow S. Desmoid tumour in familial adenomatous polyposis. A review of literature. Fam Cancer. 2001; 1:111-9.

Casillas J, Sais G, Greve J, Iparraguirre M, Morillo G. Imaging of intra- and extra -abdominal desmoid tumors. Radiographics. 1991; 11: 959-68.

Kingston C, Owens C, Jeans A, Malone M. Imaging of desmoid fibromatosis in pedriatric patients. AJR. 2002;178:191-9.

Faria S, Iyer R, Rashid A, Ellis L, Whitman G. Desmoid tumor of the small bowel and the mesentery. AJR. 2004;183:118.

Vandervenne J, De Schepper A, De Beuckeleer L, Marck E, Aparisi F, Bloem J. New concepts in understanding evolution of desmoid tumor: MR imaging of 30 lesions. Eur Radiol. 1997;7:1031-19.

Lee J, Thomas J, Phillips S, Fisher C, Moskovic E. Aggressive fibromatosis: MRI features with pathologic correlation. AJR. 2006; 186: 247-54.

Rosen R, Kimbell W. Extra-abdominal desmoid tumor. Radiology. 1966;86:534-40.

Downloads

Published

2023-09-07

How to Cite

1.
YAMRUBBOON W, PHONGKITKARUN S, JAOVISIDHA S, SIRIKULCHAYANONTA V, TAPANEEYAKORN J. DEEP FIBROMATOSIS (DESMOID TUMOR) IN THE TRUNK AND ABDOMEN: CT/MRI AND PATHOLOGICAL FINDINGS. ASEAN J Radiol [Internet]. 2023 Sep. 7 [cited 2024 Nov. 21];13(1):11-20. Available from: https://asean-journal-radiology.org/index.php/ajr/article/view/780

Issue

Vol. 13 No. 1 (2007): January-April

Section

Original Article

License

Copyright (c) 2023 The ASEAN Journal of Radiology

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Disclosure Forms and Copyright Agreements
All authors listed on the manuscript must complete both the electronic copyright agreement. (in the case of acceptance)

Most read articles by the same author(s)

1 2 > >>