ADDITIONAL DATA OF LEFT VENTRICULAR FUNCTION FROM 16 SLICED MDCT IN PATIENTS WHO UNDERWENT CORONARY CTA: COMPARING WITH ECHOCARDIOGRAPHY

Abstract

PURPOSE: Tocompare the left ventricular (LV) function data obtained from coronary computed tomography angiography (CTA) to the data obtained from echocardiography.

MATERIAL and METHODS: Twenty patients (15 males and 5 females) with mean age of 62.9 years (49 to 79 years) were performed coronary CTA using 16 sliced multi-detector computed tomography, with 8 cardiac phases of data collection and echocardiography within an average of 5.5 day period without intervening acute cardiac event or any intervention between CTA and echocardiographic study. The LV function data was calculated semiautomatedly using vendor software, including ejection fraction (EF), end systolic volume (ESV), end diastolic volume (EDV), and stroke volume (SV). The wall motion evaluation was obtained, using short axis CINE loop at the apical, middle, and basal segments. The study was reviewed by experienced cardiac radiologists. The data was compared with data from echocardiography.

RESULT: Good correlation of the EF was found between CTA and echocardiography, with concordance correlation coefficient of 0.7. Mean EF of CTA and echocardiography were 69.8+/-9.0 (48.5 to 83.5) and 68.3+/-7.9 (46.7 to 81.3), respectively.
High agreement of CINE LV wall motion evaluation between CTA and echocardiography was found, with overall agreement of 92.81% (297 in 320 segments), and negative predictive value of 98.66%(295 in 299 segments).
Additional data of LV function was also obtained from CTA, including EDV 94.1 +/-23.8 (53.4 to 146.5), ESV 29.3+/-13.1 (8.8 to 54.6), and SV 65.3+/-15.6 (44.6 to 93.9).

CONCLUSION: Good correlation of EF and high agreement of CINE LV wall motion evaluation between CTA and echo were found. LV function analysis data can be used as a reliable noninvasive imaging modality and also as an addition to noninvasive coronary CTA in single study.