CASE SERIES: COMPENSATED HYPOTHYROIDISM PRESENTED AS SIMPLE GOITRE
Abstract
A lady of age 23 years from Babukhan, Rangpur came to our centre for estimation of thyroid hormones (tri-iodothyronine, T3 & thyroxine,T4) and thyrotropin (thyroid stimulating hormone, TSH) on 4 Oct. 2001. She had high TSH, but normal T3 & T4 which is known as compensated hypothyroidism. She had a small goitre and was given thyroxine tablets 50 to 100 micrograms (mcg) per day, but her TSH level was found to be very high on 19 Feb. 2002, most probably due to irregular thyroxine intake (Table 1). She had a fine needle aspiration cytology (FNAC) from her neck mass on 30 April 2002 which revealed benign nature of her goitre. She stopped thyroxine in January 2003 and her goitre aggravated as confirmed by thyroid scintigraphy using technetium (Tc-99m) under computerized gamma camera on 26 July 2003 (Fig.1). She was advised to start thyroxine again.
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Thilly CH, Bourdoux P, Contempre B, Swennen B, Strategies for combating endemic goitre and iodine deficiency disorders (IDD).1988 No.175/176 Children in the tropics. International Children ’s Centre, Paris pp. 5-68.
British National Formulary No. 32 Sept. 1996, p. 297. British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Safrit HF. Thyroid disorders. In Fitzgerald PA (ed.) : Handbook of clinical endocrinology. 1986 Jones Med. Pub. Greenbrae, CA pp. 122-169.
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