MATHEMATICAL MODEL FOR VITAMIN B12 AND FOLATE FROM RIA CORRELATION CURVE, A SHORT REPORT

Abstract

Good nutrition is an important aspect of healthy living. Blood levels of vitamin B12 and folate are key markers of an individual’s nutritional status. Laboratory support for the diagnosis and management of these multiple clinical entities is controversial and somewhat problematic. Although, the radioimmunoassay can be a useful reliable tool to perform these two tests but it is not easily available. Nevertheless, it is very expensive and seems not cost effective for the present situation of economic crisis. Here, we developed a new mathematical model to be an alternative for determination of estimated level of vitamin B12 and folate. The first model for vitamin B12 can be shown as the equation plot hemoglobin (x) versus vitamin B12 (Y): Y = 1.7X + 252. The second model for folate can be shown as the equation plot hemoglobin (x) versus folate (Y): Y = 1.4X - 6.2. The reference range for vitamin B12 and folate from our method are similar to the reference range by RIA in the text. However, before the conclusion to state that this model is an effective model, an in depth analysis of this new method as MAY. - AUG, 2002. Volume VIII Number II the comparative study including to the cost effectiveness analysis is recommended.