CT AND MRI OF THE BRAIN IN WILSON DISEASE (WILSON'S DISEASE)
Abstract
Two cases of Wilson disease were presented. One case was 14 years old girl, had low density at pons, midbrain, thalamus, putamen and brain atrophy. New low density lesions and expanded areas of the previous low density areas were noted by CT scan after 4 months follow up. Another case of 31 years old male, his pons and thalamus contained bright signal on T2WI-MRI study. Brain atrophy, mild ventriculomegaly, were seen. Low signal at red nucleus, substantia nigra, globus pallidus and dentate nuclei was shown on T2WI-MRI study.
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Wyngaarden, Smith, Bennett. Cecil Textbook of medicine. Philadelphia: W.B. Saunders Company, 1992:1132-1133.
Brugieres P, Combes C, Ricolfi F, Degos JD, Poirier J, Gaston A. Atypical MR presentation of Wilson disease: A possible consequence of paramagnetic effect of copper? Neuroradiology 1992;34:222-224.
Robbins SL, Cotran RS, Pathologic basis of disease. 2nd ed. Philadelphia: Saunders, 1979:1592.
Finlayson MH, Superville B. Distribution of cerebral lesions in acquired hepatocerebral degeneration. Brain 1981;79-95.
Duchen LW, Jacobs JM. Familial hepatolenticular degeneration (Wilson's disease). in: Adams JH, Corsellis AN, Duchen LW, eds. Greenfield's neuropathology. 4th ed. London: Edward Arnold, 1984:595-599.
Imiya M, Ichikawa K, Matsushima H, Kageyama Y, Fujioka A. MR of the base of the pons in Wilson disease. AJNR 1992;13:1009-1012.
Schulman S. Wilson's disease. In: Minckler J, ed. Pathology of the nervous system. New York: Mc Graw Hill, 1968:1089-1103.
Goebel HH, Herman-Ben Zur P. Central pontine myelinolysis. In: Vinken PJ, Brryyun GW, ed. Handbook of clinical neurology. Amsterdam:North-Holland Publishing Co, 1976;28:285-316.
Nishiyama S, Watanabe K, Abe H. A case of Wilson's disease with central pontine myelinolysis. Shinkei Kenkyu no Shinpo 1966;10:159-160.
Matsuoka T, Miyoshi K, Hayashi S, Kageyama N. Central pontine myelinolysis: a report of three cases. Acta Neuropathol (Ben) 1965;5:117-132.
Gocht A, Colmant HJ. Central pontine and extrapontine myelinolysis: a report of 58 cases. Clin Neuropathol 1987;6:262-270.
Wilson SAK: Progressive lenticular degeneration: a familial nervous disease associated with cirrhosis of the liver. Brain 1912;34:295.
Menkes JH: Disorders of metal metabolism. P. 426. In Rowland LP (ed): Merritt's Textbook of Neurology, 7th Ed. Lea & Febiger, Philadelphia, 1984.
Elster AD. Cranial magnetic resonance imaging. New York: Churchill Livingstone, 1988:226-227.
Schulman S: Wilson's disease. p. 1113. In Minckler J (ed): Pathology of the Nervous system. McGraw-Hill, New York, 1968.
Kvicala V, Vymazal J, Nevsimalova S: Computed tomography of Wilson's disease AJNR 1983;4:429.
Kendall BE, Pollock SS, Bass NM, Valentine AR: Wilson's disease. Clinical correlation with cranial computed tomography. Neuroradiology 1981;22:1.
Williams JB, Walsche JM: Wilson's disease: analysis of the cranial computerized tomographic appearances found in 60 patients and the changes in response to treatment with chelating agents. Brain 1981;104:735.
Aisen AM, Martel W, Gabrielsen TO et al: Wilson disease of the brain: MR imaging. Radiology 1985;157-137.
Lawler GA, Pennock JM, Steiner RE et al: Nuclear magnetic resonance (NMR) imaging in Wilson disease. J Comput Assist Tomogr 1983;7:1.
Starosta-Rubenstein S, Young AB, Kluin K et al: Quantitative clinical assessment of 25 Wilson's patients: correlation with structural changes on MRI. Neurology 1985;35:175.
Sener RN. The claustrum on MRI: normal anatomy, and the bright claustrum as a new sign in Wilson's disease. Pediatr Radiol 1993;23:594- 596.
Runge VM, Clanton JA, Smith FW, et al. Nuclear magnetic resonance of iron and copper disease states. AJR 1983;141:943-948.
Drayer BP, Olanow W, Burger P, et al. Parkinson syndrome: diagnosis using high field MR imaging of brain. Radiology 1986;159:493-498.
Greenfield's neuropathology. Arnold, London 1976, pp 172-177.
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