@article{Pusuwan_Ekjeen_Tocharoenchai_Maungsomboon_Wiyaporn_Komoltri_Ruangma_Tiparoj_2019, place={Bangkok, Thailand}, title={A Comparison of Bone Scan Using between F-18 NaF PET/CT and Tc-99m MDP}, volume={19}, url={https://asean-journal-radiology.org/index.php/ajr/article/view/25}, DOI={10.46475/aseanjr.v19i2.25}, abstractNote={<p><strong>Objective: </strong>To study bone scintigraphy using between F-18 NaF PET/CT and Tc-99m MDP scan for detecting bone metastases.</p> <p><strong>Material and Methods:</strong> Thirteen patients (5 males, mean age 55.4 years, range 34-74 years) who were suspected bone metastases with single or two equivocal lesions on Tc-99m MDP bone scan were recruited between October 2010 and October 2012. All these patients underwent F-18 NaF PET/CT scan within one week after Tc-99m MDP bone scan. The sensitivity, specificity and accuracy of Tc-99m MDP bone scan and F-18 NaF PET/CT in differentiating metastatic bone lesion from benign lesion by patientbased and lesion-based analyses were studied.</p> <p><strong>Results:</strong> F-18 NaF PET/CT could identify all seven patients with malignant bone metastases that Tc-99m MDP bone scan was interpreted as malignancy in only three patients (42.9%) and equivocal in the rest of these patients. For lesion-based analysis of the overall 75 lesions, the sensitivity, specificity and accuracy of Tc-99m MDP bone scan were 48%, 83.3% and 70.7% and F-18 NaF PET/CT were 100% for all parameters. Besides the ability of F-18 NaF PET/CT to accurately identify malignancy from benign lesion, unenhanced CT portion of PET/CT can show extra-osseous findings that may change patient management.</p> <p><strong>Conclusion:</strong> F-18 NaF PET/CT provides an excellent bone image quality and higher accuracy than Tc-99m MDP bone scan. Then F-18 NaF PET/CT is a good choice for evaluating bone metastases.</p>}, number={2}, journal={The ASEAN Journal of Radiology}, author={Pusuwan, Pawana and Ekjeen, Tawatchai and Tocharoenchai, Chiraporn and Maungsomboon, Kobkun and Wiyaporn, Kanyalak and Komoltri, Chulalak and Ruangma, Ananya and Tiparoj, Ruentip}, year={2019}, month={Mar.}, pages={77–87} }